False negative diagnosis of PD in three cases on blinded video review: reviewer 2
False Negatives | Blinded video Diagnosis | Clinical features leading to diagnosis | FP-CIT result | Drugs at time of video | ||||
NPRT | NFB | MF | NGI | DF | ||||
Case 9 | DT | − | + | − | − | + |
| 12 months on L-dopa 300 mg/day |
Case 34 | DT | − | + | − | − | − |
| 8 months on L-dopa 300 mg/day |
Case 35 | DT | + | + | − | − | + |
| Drug naive |
Congruent refers to predominant FP-CIT abnormality contra-lateral to most affected clinical side.
DF, dystonic features, for example collis, thumb hyperextension, shoulder elevation; DT, dystonic tremor; FP-CIT, N-ω-fluoro-propyl- 2ß-carbomethoxy-3ß-(4-iodophenyl) nortropane; JP and JB refer to nuclear physicians across the two sites; MF, myoclonic flurries; NFB, no fatiguable bradykinesia; NGI, no gait impairment; NPRT, no pill rolling rest tremor PD, Parkinson's disease.