Table 2

Results of daily rated outcome measures (OM): baseline values (14-day run-in period)

Baseline (means, SD)Treatment (means, SD)Difference*95% CIp Value
Sequence 1/0Sequence 0/1PlaceboTetrahydrocannabinol
Primary OM
Cramp intensity4.12
1.76
3.80
0.92
3.49
1.37
3.69
1.70
0.24−0.32 to 0.810.38
Secondary OM
Fasciculation intensity4.83
2.27
3.92
1.09
3.66
1.86
4.02
1.94
0.43−0.26 to 1.110.21
No of cramps/day (24 h)3.44
1.43
4.89
3.15
3.05
2.49
3.29
3.37
0.24−0.69 to 1.180.59
No of cramps/daytime2.12
1.24
3.00
3.37
1.82
1.75
2.09
2.80
0.27−0.53 to 1.070.49
No of cramps/bedtime1.32
0.87
1.97
1.34
1.40
1.29
1.27
1.32
−0.06−0.54 to 0.420.80
  • * Differences in estimated treatment effects are adjusted for period, sequence and baseline.