Table 3

Results of outcome measures rated after each treatment period at each study visit

Secondary outcome measuresBaseline (means, SD)Treatment (means, SD)Difference*95% CIp Value
Sequence 1/0Sequence 0/1PlaceboTetrahydrocannabinol
ALS Assessment Questionnaire- 40103.30
33.87
92.09
38.89
91.86
42.60
103.00
29.39
11.55−8.35 to 31.460.24
Sleep Disorder Questionnaire12.11
6.67
14.86
3.48
12.39
6.39
14.59
4.15
2.14−0.90 to 5.180.16
Functional Assessment of Anorexia/Cachexia Therapy12.75
3.68
9.95
2.42
11.05
3.32
11.52
3.46
0.51−0.97 to 2.000.48
Hospital Anxiety and Depression Scale10.20
6.19
9.57
5.43
9.79
5.65
10.00
6.02
0.68−2.57 to 3.920.66
  • * Differences in estimated treatment effects are adjusted for period, sequence and baseline.