Table 2

Multiple regression model to identify determinants of increased blood–brain barrier permeability in normal-appearing white matter and cerebrospinal fluid

Normal-appearing white matterCerebrospinal fluid
R20.4940.603
ANOVA
F3.1444.897
p Value0.009<0.0005
Variablesβp Valueβp Value
Age−0.1380.492−0.2930.105
Gender0.040.79−0.1850.166
Weight−0.5510.007−0.0850.619
Brain volume−0.040.8210.180.257
Leucoaraiosis grade0.3640.0270.5420.001
Area under curves in ICA−0.1340.4590.2330.152
Hypertension0.2320.164−0.0010.995
Diabetes−0.0170.913−0.1240.369
Current smoking0.1120.50.2040.172