SOD1 mutations per population
Familial disposition for amyotrophic lateral sclerosis | Sporadic amyotrophic lateral sclerosis | |||||
Country | SOD1 positive families (no) | No tested | Percentage SOD1 | SOD1 positive patients (No) | No tested | Percentage SOD1 |
USA15 | 68 | 290 | 23.4 | – | – | – |
Belgium24 | 7 | 23 | 30.4 | 2 | 69 | 2.9 |
Canada (British Columbia)9 | 10 | 47 | 21.3 | 3 | 159 | 1.9 |
Canada (French)10 | 10 | 70 | 14.3 | – | – | – |
Italy18 | 3 | 22 | 13.6 | 2 | 303 | 0.7 |
Italy19 | 7 | 39 | 17.9 | 0 | 225 | 0 |
Italy17 | 0 | 4 | 0 | 3 | 66 | 4.5 |
Italy16 | 5 | 34 | 14.7 | 2 | 44 | 4.5 |
Spain (Catalonia)20 | 5 | 30 | 16.7 | 4 | 94 | 4.3 |
France21 | – | – | 15 | – | – | – |
Scotland8 | 5 | 10 | 50 | 4 | 57 | 7 |
Ireland7 | 1 | 8 | 12.5 | 2 | 90 | 2.2 |
UK25 | 8 | 38 | 21 | 5 | 175 | 2.9 |
UK14 | – | – | – | 4 | 155 | 2.6 |
UK13 | 17 | 85 | 20 | – | – | – |
Japan11 | 5 | 7 | 71.4 | – | – | – |
Denmark22 | 2 | 2 | 100 | 1 | 25 | 4 |
Finland22 | 9 | 21 | 42.9 | 9 | 80 | 11.3 |
Norway22 | 0 | 4 | 0 | 0 | 37 | 0 |
Sweden22 | 16 | 45 | 35.6 | 4 | 213 | 1.9 |
Germany23 | 9 | 75 | 12 | – | – | – |
The Netherlands | 1 | 55 | 1.8 | 2 | 451 | 0.4 |