Correlation between annual changes in EDSS, and PBVC and PVVC for both time intervals
| Annual EDSS change 0–2 years | Annual EDSS change 2–5.5 years | ||
| aPBVC 0–2 | ρ | −0.29 | −0.08 |
| p Value | * | NS | |
| aPBVC 2–5.5 | ρ | −0.01 | −0.01 |
| p Value | NS | NS | |
| aPVVC 0–2 | ρ | 0.28 | 0.13 |
| p Value | * | NS | |
| aPVVC 2–5.5 | ρ | 0.08 | 0.18 |
| p Value | NS | NS |
*p<0.05; **p<0.01.
0–2, time interval between baseline and 2 years of follow-up; 2–5.5, time interval between 2 and 5.5 years of follow-up; aPBVC, annual percentage brain volume change; aPVVC, annual percentage ventricular volume change; EDSS, Expanded Disability Status Scale.