Table 1

Main demographic and clinical characteristics of the six groups of subjects studied

Paediatric healthy volunteersAdult healthy volunteersPaediatric CIS patientsPaediatric RRMS patientsAdult CIS patientsAdult RRMS patients
No of subjects151810383027
Women/men10/511/76/424/1421/918/9
Mean age (range) (years)14.7 (9 to 18)37.4 (26 to 60)15.1 (12 to 18)14.7 (7 to 18)34.0 (24 to 56)41.3 (28 to 60)
Median Expanded Disability Status Scale score (range)1.0 (1.0 to 1.5)1.0 (0.0 to 2.5)1.0 (0.0 to 2.5)1.5 (0.0 to 3.0)
Mean disease duration (range) (years)1.4 (0.3 to 4.9)4.6 (1.2 to 8.0)0.2 (0.1 to 0.25)5.9 (2.1 to 9.8)
Therapy: IFNβ1a/glatiramer acetate/mitoxantrone)5/0/023/3/17/2/014/1/1
  • CIS, clinical isolated syndrome; IFNβ1a, interferon β 1a; RRMS, relapsing remitting multiple sclerosis.