Group values of clinical variables of hand function and manual dexterity
| Charcot–Marie–Tooth disease type 1A n=49 | Multifocal motor neuropathy n=15 | ||||
| Mobility of the fingers | Impaired active range of motion | n (%) | D | 18 (37) | 12 (80) |
| ND | 13 (27) | 13 (87) | |||
| Clawing of the fingers | n (%) | D | 13 (27) | 8 (53) | |
| ND | 11 (22) | 7 (47) | |||
| Impaired passive range of motion | n (%) | D | 3 (6) | 3 (20) | |
| ND | 2 (4) | 2 (13) | |||
| Impaired opposition | n (%) | D | 25 (51) | 11 (73) | |
| ND | 20 (41) | 10 (67) | |||
| Sensory modalities | Threshold for touch (Semmes Weinstein Monofilaments, mean of seven localisations) | Mean±SD, range | D | 3.62±0.33, 2.89–4.32 | 3.37±0.19, 3.05–3.68 |
| ND | 3.57±0.32, 2.89–4.25 | 3.35±0.26, 2.83–3.74 | |||
| Static two-point discrimination (mm) | Mean±SD, range | D | 5.18±2.27, 2–16 | 4.4±2.67, 2–12 | |
| ND | 4.76±2.80, 2–20 | 4.3±2.46, 2–12 | |||
| Impaired vibration sense | n (%) | D | 10 (20) | 1 (7) | |
| ND | 7 (14) | 1 (7) | |||
| Hand strength | Grip (N) | Mean±SD, range | D | 245±122, 42–544 | 166±132, 13–458 |
| ND | 237±117, 39–533 | 170±119, 5–449 | |||
| Two-point pinch (N)* | Mean±SD, range | D | 31±20, 0–78 | 17±24, 0–64 | |
| ND | 33±19, 0–80 | 15±19, 0–56 | |||
| Tripod pinch (N)* | Mean±SD, range | D | 43±28, 0–102 | 26±40, 0–105 | |
| ND | 44±26, 0–96 | 21±24, 0–66 | |||
| Lateral pinch (N) | Mean±SD, range | D | 47±24, 6–102 | 41±32, 3–100 | |
| ND | 47±23, 7–112 | 38±25, 2–79 | |||
| Manual dexterity | Sollerman hand function test sum score | Median (P25; P75), range | D | 76 (67.5; 78), 33–80 | 48 (43; 68), 27–80 |
| ND | 76 (69; 77.5), 41–80 | 50 (44; 67), 19–77 | |||
↵* If a patient was not able to perform a two-point or tripod pinch, a score of 0 N was recorded.
D, dominant hand; ND, non-dominant hand.