Table 2

Age and gender specific incidence of amyotrophic lateral sclerosis per 100 000 person years among those 18 years and over based on combined data from the six European amyotrophic lateral sclerosis registers for the 2 year period, 1998–1999

Age (years)*MenWomenTotal
Cases†Person year‡Incidence§95% CICasesPerson yearIncidence95% CICasesPerson yearIncidence95% CI
18–192596 3280.30.0 to 0.80571 361--21 167 6880.20.0 to 0.4
20–2411 563 7780.10.0 to 0.211 525 6770.10.0 to 0.223 089 4550.10.0 to 0.2
25–2961 720 2250.30.1 to 0.661 706 4320.40.1 to 0.6123 426 6570.40.2 to 0.5
30–3451 856 3980.30.0 to 0.521 859 1550.10.0 to 0.373 715 5530.20.0 to 0.3
35–39111 869 1350.60.2 to 0.931 885 4450.20.0 to 0.3143 754 5800.40.2 to 0.6
40–44241 693 8961.40.8 to 2.0141 710 5340.80.4 to 1.2383 404 4301.10.8 to 1.5
45–49351 565 1272.21.5 to 3.0231 582 2621.50.9 to 2.0583 147 3891.81.4 to 2.3
50–54381 606 0432.41.6 to 3.1371 615 7722.31.6 to 3.0753 221 8152.31.8 to 2.9
55–59771 348 1485.74.4 to 7.0391 385 1522.81.9 to 3.71162 733 3004.23.5 to 5.0
60–64721 280 4965.64.3 to 6.9791 367 3025.84.5 to 7.11512 647 7985.74.8 to 6.6
65–69951 098 0738.76.9 to 10.4841 261 8656.75.2 to 8.11792 359 9387.66.5 to 8.7
70–7496900 35210.78.5 to 12.8761 170 2786.55.0 to 8.01722 070 6308.37.1 to 9.5
75–7963649 5479.77.3 to 12.169990 2657.05.3 to 8.61321 639 8118.06.7 to 9.4
80–8424324 6767.44.4 to 10.324602 6544.02.4 to 5.648927 3305.23.7 to 6.6
>855245 4992.00.3 to 3.817643 6152.61.4 to 3.922889 1132.51.4 to 3.5
Total55418 317 7223.02.8 to 3.347419 877 7682.42.2 to 2.6102838 195 4872.72.5 to 2.9

  • ↵* Age at diagnosis.

  • ↵† No of cases of ALS diagnosed in the six European ALS registers for the 2 year period, 1998–1999.

  • ↵‡ Combined person years for the six European for the 2 year period, 1998–1999.

  • ↵§ Per 100 000 person years.

  • ALS, amyotrophic lateral sclerosis.