No of patients | Per cent of patients | |
Weakness | 75 | 100 |
Distal | 73 | 97 |
Distal predominant | 70 | 93 |
Asymmetric | 70 | 93 |
Arms | 73 | 97 |
Arm predominant | 71 | 95 |
Leg predominant | 2 | 3 |
MMN | 23 | 31 |
Conduction block | 42 | 56 |
Conduction block, or IgM versus GM1 or NS6S | 62 | 83 |
Sensory loss, legs | 28 | 37 |
SNAPs abnormal, legs | 16 | 21 |
IgM M-protein | 17 | 23 |
Clinical and laboratory features in the motor neuropathy group (75 patients). Most patients had distal, asymmetric, arm predominant weakness.
Conduction block, motor conduction block4 found in at least one location at a non-entrapment site along the length of a nerve; Conduction block, or IgM versus GM1 or NS6S, presence of at least one of motor conduction block or high titre IgM binding to NS6S or GM1 ganglioside; IgM M-protein, IgM M-protein present in serum detected by immunofixation methodology; MMN, multifocal motor neuropathy, consensus criteria4; SNAPs abnormal, sensory nerve action potentials absent or reduced amplitude.