Clinical characteristics† |
Mean age in years (range) | 70±10.5 (52–86) | 66±10.6 (41–87) | NS |
Men, N (%) | 10 (62.5) | 18 (54.5) | NS |
Hypertension (%) | 12 (75) | 27 (81.8) | NS |
Systolic blood pressure (mm Hg) | 165±26 | 151±32 | NS |
Diastolic blood pressure (mm Hg) | 87±12 | 83±16 | NS |
Diabetes (%) | 4 (25) | 2 (6.1) | NS |
Cholesterol total >6 mmol/l (%) | 1 (6) | 2 (6) | NS |
Statin use (%) | 5 (31) | 4 (13) | NS |
Ischaemic heart disease (%) | 6 (37.5) | 1 (3) | 0.003* |
Atrial fibrillation (%) | 2 (12.5) | 3 (9.1) | NS |
Previous stroke (%) | 8 (50) | 2 (6.1) | <0.001* |
Smoking (%) | 10 (62.5) | 10 (30.3) | NS |
Median interval stroke-MRI in days (range) | 11 (2–115) | 7 (0–222) | NS |
Imaging characteristics |
Microbleeds |
Presence (%, range) | 13 (81.2, 0–28) | 15 (45.4, 0–31) | 0.030* |
Median (range) | 6.0 (0–28) | 0.0 (0–31) | 0.012* |
Lobar |
Presence (%) | 11 (69) | 11 (33) | 0.032* |
Median (range) | 3.0 (0–15) | 0 (0–12) | 0.016* |
Deep (basal ganglia and thalamus) |
Presence (%) | 9 (56.2) | 9 (27.3) | NS |
Median (range) | 1.0 (0–11) | 0 (0–17) | 0.032* |
Posterior fossa (brainstem and cerebellum) |
Presence (%) | 6 (37.5) | 5 (15) | NS |
Median (range) | 0 (0–2) | 0 (0–8) | NS |
Lacunes |
Presence (%) | 12 (80) | 24 (75) | NS |
Median (range) | 2.0 (0–9) | 2.0 (0–7) | NS |
Leucoaraiosis |
Presence (%) | 8 (50) | 8 (24) | NS |