Table 4

Likelihood of EDSS ≥4.0 versus EDSS <4.0 according to level of deseasonalised serum 24,25(OH)2VD3

Deseasonalised 24, 25(OH)2VD3 levels (ng/ml)EDSS ≥4.0EDSS <4.0Adjusted OR (95% CI)*
n (%)n (%)
>5.0333 (23.7%)6 (11.5%)1.0†
3.10–5.0230 (21.6%)8 (15.4%)1.43 (0.41 to 5.02)
2.52–3.5232 (23.0%)10 (19.2%)1.56 (0.46 to 5.23)
1.71–2.5523 (16.5%)15 (28.8%)4.88 (1.48 to 16.1)
<1.7121 (15.1%)13 (25.0%)3.72 (1.07 to 12.9)

  • The linear trend had p=0.006.

  • ↵* Logistic regression models adjusted for sex, race, age at blood draw and duration of disease.

  • ↵† Reference category.

  • EDSS, Expanded Disability Status Scale.