Clinical manifestations, investigations and subtypes of osmotic demyelination syndrome (n=25)
| Variable | No (%) |
| Mean age at presentation (years, SD) | 53.3±14.5 |
| Male:female | 11:13 |
| Encephalopathy at presentation | 20 (80) |
| Seizures | 9 (36) |
| Mute state | 8 (32) |
| Extrapyramidal syndrome | 15 (60) |
| Extraocular movement abnormality | 9 (36) |
| Deep tendon reflexes (brisk:hypo/areflexia) | 6:8 |
| Abnormality in EEG (n=12) | 8 (66.7) |
| Neuropathy in nerve-conduction study (n=6) | 4 |
| Treatment (intravenous methylprednisolone) | 6 (24) |
| Diagnosis | |
| Central pontine myelinolysis | 5 (20) |
| Extrapontine myelinolysis | 7 (28) |
| Combination | 13 (52) |