Time to the disability endpoints according to duration of IFNB-1b treatment
| Duration of time on IFNB-1b treatment | |||
| <10% | 10–79% | ≥80% | |
| Patients reaching EDSS ≥6.0, N (%) | 27 (38.6) | 76 (46.9) | 10 (35.7) |
| Patients reaching SPMS, N (%) | 24 (34.3) | 72 (44.4) | 8 (28.6) |
| Patients with EDSS ≥6.0 or SPMS, N (%) | 35 (50.0) | 94 (58.0) | 11 (39.3) |
| Median time from onset of symptoms to EDSS 6.0 (y)* | 12.40 | 14.95 | 20.10 |
| Median time from onset of symptoms to SPMS 6.0 (y)* | 14.25 | 16.60 | 18.80 |
↵* Only calculated for patients who reached these endpoints.
EDSS, Expanded Disability Status Scale; SPMS, secondary progressive multiple sclerosis.