With seizures | Without seizures | ||
Early seizures | Late seizures* | ||
N=27 | N=21 | N=157 | |
Mean age, y | 44.5±18.3 | 49.8±17.5 | 45.8±18.2 |
Sex (male/female) | 19/8 | 16/5 | 116/49 |
Mean GCS on presentation | 15 | 15 | 15 |
Clinical features following brain abscess | |||
Fever/chills | 17 | 16 | 94 |
Headache | 13 | 12 | 90 |
Disturbed consciousness | 10 | 10 | 70 |
Septic shock | 6 | 4 | 20 |
Sensory disturbance | 2 | 5 | 22 |
Hemiparesis | 17 | 9 | 70 |
Visual disturbance | 3 | 2 | 23 |
Nausea/vomiting | 8 | 5 | 46 |
Neck stiff neck | 6 | 7 | 51 |
Facial palsy | 1 | 1 | 11 |
Speech disturbance | 1 | 2 | 4 |
Treatment | |||
Antimicrobial treatment only | 9 | 4 | 30 |
Combination of surgical and antimicrobial treatment | 18 | 17 | 127 |
Outcome | |||
Death | 9 | 2 | 32 |
Median (IQR)length of hospitalisation (days) | 44 (21–91) | 48.5 (31–86.3) | 42 (25.8–60.2) |
Median (IQR) GOS at discharge | 3 (1.3–5) | 4 (2–5) | 4 (2–5) |
Median (IQR) GOS at the end of the study | 5 (1–5) | 5 (5–5) | 5 (5–5) |
↵* Thirteen patients had unprovoked seizures after discharge.
GCS, Glasgow Coma Scale; GOS, Glasgow Outcome Scale; IQR, interquartile range.