Characteristics | Decompression after intra-arterial thrombolysis (n=15) | Decompression without prior thrombolysis (n=15) | p-Value |
Age, years (SD) | 49.2 (12.8) | 50.0 (7.0) | NS |
Female sex, n (%) | 7 (47) | 7 (47) | NS |
Vascular risk factors, n (%) | |||
Hypertension | 5 (33) | 6 (40) | NS |
Diabetes mellitus | 1 (7) | 0 | NS |
Current smoking | 4 (27) | 5 (33) | NS |
Hypercholesterolaemia | 9 (60) | 4 (27) | NS |
Coronary artery disease | 6 (40) | 2 (13) | NS |
Atrial fibrillation | 1 (7) | 1 (7) | NS |
Previous transient ischemic attack | 0 | 1 (7) | NS |
Previous stroke | 1 (7) | 1 (7) | NS |
Previous transient monocular blindness | 0 | 0 | NS |
Family history of stroke | 3 (20) | 5 (33) | NS |
Family history of myocardial infarction | 2 (13) | 2 (13) | NS |
National Institute of Health Stroke Scale score on admission, median (range) | 17 (12–28) | 14 (10–36) | 0.033 |
Stroke aetiology, n (%) | |||
Large artery disease | 3 (20) | 3 (20) | |
Cardioembolic | 4 (27) | 1 (7) | |
Other determined aetiology | 0 | 6 (40) | |
Unknown aetiology | 8 (53) | 5 (33) | |
More than one cause | 0 | 0 | |
Mechanical thrombaspiration, n (%) | 5 (33) | 6 (40) | NS |
Mean time (h) from symptom onset to decompression (SD) | 26.7 (14.4) | 23.8 (17.6) | NS |
Outcome, n (%) | NS | ||
Modified Rankin Scale 0–3 | 7 (47) | 4 (27) | |
Modified Rankin Scale 4–6 | 8 (53) | 11 (73) | |
Mortality, n (%) | 4 (27) | 3 (20) | NS |
Major complications after surgery, n (%) | 3 (20) | 7 (47) | NS |
Minor complications after surgery, n (%) | 5 (33) | 6 (40) | NS |
Fifteen patients underwent thrombolysis prior to decompression, and 15 patients were not thrombolysed. A two-sided p value <0.05 was considered statistically significant.
NS, not significant.