Table 3

Profile of aquaporin-4 antibody-positive patients in relapsing-remitting clinical course without optic neuritis or myelitis

CaseAge at onset/genderLesion of first attackLesions involved in whole clinical courseNo of relapsesDisease duration (year)Complicated systemic diseasesAutoantibodyMRI cerebral lesion
No of lesionsOvoid lesionsubcallosal lesion
151FCbrCbr, BS35(−)ANA, SS(+)4∼8(+)(−)
335FCbrCbr, BS22Hyper-thyroidismANA, SS(−)
421MCbr, BSCbr, BS31Hashimoto's chronic thyroiditisANA(+)4∼8(+)(+)
519FBSBS, cerebellum*32(−)ANA, SS(−)
640FBSCbr22(−)ANA, SS(−)
723FBSCbr, BS44(−)ANA(+)NANANA
  • * Lesion detected on MRI alone.

  • ANA, antinuclear antibody; AQP4-ab, aquaporin 4 antibody; BS, brainstem; Cbr, cerebrum; F, female; M, male; NA, data not available; SS, SS-A/Ro antibody and/or SS-B/La antibody.