Amyotrophic lateral sclerosis (n=334) | Controls (n=538) | |
Median age*, years (range) | 60 (24 to 82) | 59 (29 to 89) |
Female, n (%) | 145 (43) | 246 (46) |
Site at onset, n (%) | ||
Bulbar | 86 (27) | |
Spinal | ||
Cervical | 114 (36) | |
Thoracal | 4 (1) | |
Lumbosacral | 102 (32) | |
Multiple regions | 13 (4) |
↵* Age at onset was used in the multivariate analysis.
All patients fulfilled the El Escorial criteria for probable and definite amyotrophic lateral sclerosis.