Association between survival in amyotrophic lateral sclerosis and low-density lipoprotein/high-density lipoprotein ratio
| All | Women | Men | ||||
| HR | p Value | HR | p Value | HR | p Value | |
| Univariate regression | 0.9 | 0.04* | 1.0 | 0.9 | 0.8 | 0.01* |
| Multivariate regression† | 0.9 | 0.2 | 1.0 | 0.8 | 0.8 | 0.05 |
| Multivariate regression‡ | 0.9 | 0.2 | 1.0 | 1.0 | 0.9 | 0.2 |
Interpretation: HR shows the risk of decreased survival per each unit increment in serum values. Example: an increase of 1 in low-density lipoprotein/high-density lipoprotein ratio results in a 0.8× decreased survival in men (=longer disease duration).
↵* p<0.05 was considered significant.
↵† Computed by Cox regression adjusting for age and site of onset.
↵‡ Computed by Cox regression adjusting for age and site of onset and functional vital capacity percentage of predicted.