Table 2

Demographic and clinical characteristics according to CSF pattern

VariablesCBS (n=30)CBSCBS with SPECT study available
nAD-like (n=24)AD-like (n=6)p ValuenAD-like (n=18)AD-like (n=5)p Value
Age at evaluation (years)63.5±8.963.6±9.863.0±4.00.88262.2±10.463.6±4.20.779
Gender (F%)30.033.316.70.42638.900.095
Age at onset (years)61.0±9.360.9±10.361.6±4.30.86560.6±11.062.2±4.60.768
Education (years)6.6±2.96.95±3.25.3±0.80.2387.2±3.25.4±0.90.235
Family history (%)13.312.516.70.7885.620.00.311
Side at onset (left%)60.054.283.30.41750.080.00.231
APO E (ε4%)23.320.833.30.51727.840.00.599
CSF markers
 CSF abeta (pg/ml)748.2±431.5865.2±402.5280.2±77.30.002889.9±412.5266.1±77.20.003
 CST tau (pg/ml)409.1±285.3337.7±242.5694.7±281.70.004308.1±223.1726.5±302.70.002
 CSF tau/abeta ratio0.86±1.030.43±0.292.60±1.20<0.0010.44±0.462.83±1.10<0.001
  • AD, Alzheimer's disease; CBS, corticobasal syndrome; nAD-like, non-Alzheimer's disease-like; SPECT, single photon emission computed tomography.