Clinical and MRI parameters in patients with relapsing–remitting multiple sclerosis and relapsing–remitting multiple sclerosis with epilepsy at T0
| RRMS (n=60) | RRMS/E (n=32) | p Value | |
| Female: male (ratio) | 42:18 (2.3) | 15:17 (0.9) | <0.001 |
| Age (years)* | 38.0±8.9 (18–55) | 38.0±9.0 (18–55) | 0.993 |
| Disease duration (years)* | 6.0±4.8 (1–12) | 6.6±4.2 (1–15) | 0.793 |
| EDSS (median (range)) | 1.5 (1.0–5.0) | 2.5 (1.0–6.0) | <0.001 |
| T2WMLV (cm3)* | 5.4±5.3 (1.2–9.6) | 6.8±6.5 (2.1–11.0) | 0.071 |
| CEL* | 0.6±0.2 (0–3) | 0.7±0.3 (0–3) | 0.098 |
| Patients with CEL (%) | 23 (38.3%) | 11 (34.3%) | 0.707 |
| CLs number* | 4.5±2.4 (0–18) | 10.2±8.9 (0–26) | <0.001 |
| CL volume (cm3)* | 0.7±0.8 (0.2–1.5) | 2.0±1.3 (0.3–3.8) | <0.001 |
| Patients with CLs (%) | 26 (43.3%) | 27 (84.4%) | <0.001 |
| GMf (%)* | 52.5±1.3 (48.7–55.5) | 50.3±1.5 (46.0–53.2) | 0.004 |
| Global CTh (mm)* | 2.35±0.14 (2.10–2.59) | 2.12±0.19 (1.83–2.53) | <0.001 |
↵* Data are expressed as mean (SD; range).
CEL, contrast enhancing lesion; CLs, cortical lesions; CTh, cortical thickness; EDSS, Expanded Disability Status Scale; GMf, grey matter fraction; RRMS, relapsing–remitting multiple sclerosis; RRMS/E, relapsing–remitting multiple sclerosis with epilepsy; T2WMLV, T2 white matter lesion volume.