Table 3

Clinical outcomes and drug profiles at a mean of 11 years after disease onset

Total (%)Median time to outcome (years)Alive (n)Death (n)
Dementia (n (%))83 (49)134043
Psychosis (n (%))81 (47)135031
Sensory compliant (n (%))103 (60)97528
Postural hypotension (n (%))58 (34)164513
Postural instability (PIPon) (n (%))108 (63)116642
Freezing of gait (n (%))148 (87)610543
Falls (n (%))101 (59)117031
Swallowing problem (n (%))102 (60)116537
Speech disturbance (n (%))117 (68)108737
Institutionalised (n (%))46 (27)1729
Dopamine exposure (n (%))83 (49)7013
Selegiline exposure (n (%))28 (16)244
  • PIPon, postural instability persisted during ‘on’ medication state.