Characteristics of patients and healthy controls
| Control group | PD−ICB group | PD+ICB group | t value, F value, χ2 | p Value | |
| Participants in total (n) | 14 | 13 | 15 | ||
| Gender (male) | 6 | 11 | 10 | χ2=5.2, df=2 | 0.075 |
| Age (years) | |||||
| At time of testing | 58±3 | 64±2 | 56±3 | F=2.5, df=2 | 0.09 |
| At disease onset | – | 52±2 | 43±3 | t=2.6, df=24 | 0.014* |
| Disease duration (years) | – | 11±2 | 12±2 | t=0.4, df=24 | 0.7 |
| Pathological gambling | – | – | 9 | ||
| Hypersexuality | – | – | 6 | ||
| Compulsive shopping | – | – | 5 | ||
| Binge eating | – | – | 4 | ||
| Punding | – | – | 2 | ||
| Morning L-dopa dose (mg) | – | 170±22 | 185±25 | t=0.4, df=24 | 0.6 |
| Total L-dopa dose (mg) | – | 580±74 | 625±100 | t=0.3, df=24 | 0.7 |
| LEU dose (mg) | – | 722±85 | 797±100 | t=0.5, df=24 | 0.6 |
| DA (patients) | – | 8 | 5 | χ2=1.6, df=1 | 0.2 |
| UPDRS off medication | – | 25±1 | 32±4 | t=1.9, df=24 | >0.07 |
| UPDRS on | – | 14±2 | 19±3 | t=1.8, df=24 | 0.08 |
| Average improvement in UPDRS (%) | – | 44 | 41 | ||
All values are mean±SEM.
* Significant difference.
DA, dopamine agonists; ICB, impulsive compulsive behaviour; LEU, L-dopa equivalent units; PD, Parkinson's disease; UPDRS, Unified Parkinson's Disease Rating Scale.