Group | Control period (ARR) | Period before IVF (ARR) | Period following IVF (ARR) | p Value (1/3) | p Value (2/3) | ||||||
Mean | Median | Range | Mean | Median | Range | Mean | Median | Range | |||
All IVF | 0.68 (n=65) | 0 | 0–4 | 0.80 (n=70) | 0 | 0–4 | 1.60 (n=70) | 0 | 0–8 | 0.04 | 0.01 |
IVF failure | 0.82 (n=44) | 0 | 0–4 | 0.98 (n=49) | 0 | 0–4 | 1.96 (n=49) | 0 | 0–8 | 0.08 | 0.02 |
IVF success | 0.38 (n=21) | 0 | 0–4 | 0.38 (n=21) | 0 | 0–4 | 0.76 (n=21) | 0 | 0–4 | 0.56 | 0.38 |
GnRH agonists | 0.62 (n=45) | 0 | 0–4 | 0.75 (n=48) | 0 | 0–4 | 1.60 (n=48) | 0 | 0–8 | 0.03 | 0.03 |
GnRH antagonists | 0.63 (n=19) | 0 | 0–4 | 0.84 (n=19) | 0 | 0–4 | 0.84 (n=19) | 0 | 0–4 | 0.77 | 1 |
All IVF, when all IVF procedures are taken into account; IVF failure, when there was a failure of IVF to induce a pregnancy; IVF success, when IVF was followed by a pregnancy; GnRH agonists/antagonists, in patients treated with GnRH agonists/antagonists for ovarian desensitisation.
Wilcoxon paired tests were performed to compare ARR between the different periods.
ARR, annualised relapse rates; GnRH, gonadotrophin releasing hormone; IVF, in vitro fertilisation.