Table 1

Characteristics of patients who did or did not undergo non-invasive ventilation

Patients who underwent NIV (n=259)Patients who did not undergo NIV (n=1001)p ValueOR (95% CI)
Gender (M/F)164/95523/4780.0011.59 (1.19 to 2.09)
Site of onset (S/B)184/75605/3960.0041.54 (1.14 to 2.08)
Period*91/168527/4740.00012.05 (1.55 to 2.73)
EN (Y/N)109/150189/8120.00013.12 (2.32 to 4.19)
ALS centres (Y/N)197/62332/6670.00016.40 (4.68 to 8.76)
Marital status221/38710/2910.00012.38 (1.70 to 3.41)
Educational level46/213116/885NS1.65 (0.71 to 3.04)
Mean age at onset (years)61.5 (10.2)65.9 (11.3)0.0001
Mean age at diagnosis (years)62.2 (11.1)66.8 (11.3)0.0001
Mean time onset to diagnosis (months)9.9 (7.6)10.7 (9.9)0.0001
  • * Period, 1995–1999 vs 2000–2004.

  • Marital status, married versus unmarried, divorced or widow/widower.

  • Education level, high school or higher versus junior high school or lower.

  • ALS, amyotrophic lateral sclerosis; EN, enteral nutrition via percutaneous endoscopic gastrostomy or percutaneous radiological gastrostomy; NIV, non-invasive ventilation.