Table 2

Significant results of the Cox proportional hazards analysis on time to Expanded Disability Status Scale score of 6

CovariatesHR (95% CI)No of female patients with EDSS 6
YesNo
MS course
 PPMS1.005762
 RRMS0.33 (0.24 to 0.45)3051464
Age of MS onset (years)
 ≤201.0042171
 21–251.67 (1.12 to 2.48)66239
 26–301.50 (0.99 to 2.27)55330
 31–352.32 (1.53 to 3.51)65280
 36–402.55 (1.64 to 3.95)52224
 41–453.10 (1.89 to 5.11)35150
 >455.95 (3.61 to 9.80)47132
Year of birth
 <19401.0080126
 1940–491.47 (1.09 to 1.98)122272
 1950–591.54 (1.11 to 2.14)120493
 ≥19601.07 (0.68 to 1.68)40635
  • EDSS, Expanded Disability Status Scale; MS, multiple sclerosis; PP, primary progressive; RR, relapsing remitting.