Response to individual antiepileptic drug changes
| Seizure outcome* | Antiepileptic drug changes (%) N=448 |
| <50% Reduction in seizure frequency | 336 (75) |
| 50%–99% Reduction in seizure frequency | 74 (17) |
| Seizure freedom | 37† (8) |
Seizure outcome following 448 medication changes in 139 people in the extended follow-up.
↵* Outcome unknown following one additional medication change.
↵† Refers to antiepileptic drug changes in 33 people. Four people, who had at least 1 year of seizure freedom on one antiepileptic drug, attained a further period of seizure freedom on addition of a further antiepileptic drug after the original antiepileptic drug was discontinued because of relapse or side-effects.