Table 1

Florbetapir-F18 and PiB-C11 PET regional SUVRs, discrimination of AD versus CN adults, and inter-tracer correlation

Florbetapir-F18 PETPiB-C11 PETPearson Correlation n=26
CN, n=14 (SD)AD, n=12 (SD)AUC, (95% CI)Cohen dCN, n=14 (SD)AD, n=12 (SD)AUC (95% CI)Cohen d
Anterior cingulate1.12 (0.23)1.52 (0.19)0.88 (0.73 to 1.00)1.901.19 (0.27)2.35 (0.49)1.00 (0.99 to 1.00)2.930.81, (p<0.0001)
Posterior cingulate/Precuneus1.10 (0.23)1.48 (0.15)0.89 (0.74 to 1.00)1.961.15 (0.29)2.26 (0.42)0.99 (0.98 to 1.00)3.080.79, (p<0.0001)
Frontal1.00 (0.18)1.33 (0.20)0.88 (0.74 to 1.00)1.731.00 (0.26)1.90 (0.41)0.98 (0.94 to 1.00)2.620.81, (p<0.0001)
Parietal0.99 (0.16)1.15 (0.20)0.75 (0.54 to 0.96)0.880.82 (0.28)1.25 (0.30)0.85 (0.67 to 1.00)1.480.58, (p=0.002)
Lateral temporal1.11 (0.17)1.43 (0.18)0.90 (0.78 to 1.00)1.831.19 (0.18)1.92 (0.37)0.97 (0.90 to 1.00)2.510.68, (p=0.0001)
Pons1.63 (0.18)1.57 (0.12)0.41 (0.19 to 0.64)0.391.71 (0.27)1.72 (0.29)0.57 (0.34 to 0.79)0.040.38, (p=0.06)
Composite1.06 (0.17)1.38 (0.15)0.90 (0.77 to 1.00)2.001.07 (0.23)1.94 (0.36)1.00 (1.00 to 1.00)2.880.78, (p<0.0001)