Table 2

Social Cognition and Emotional Assessment performances

Tests (maximal score)Control groupMDDEarly bvFTDModerate bvFTD
SEA composite (55)47.2±3.8 (40.1–53.1)* † ‡42.6±4.8 (33.5–51.4)* § 29.2±5.7 (15.7–38.8)† 28.9±5.8 (20.5–39.4)‡ §
Emotion identification (15)12.6±1.1 (10.2–14.6)† ‡12.4±0.7 (11.6–13.7)§ 9.7±1.8 (6.8–12.9)† 8.4±2.4 (3.9–11.1)‡ §
Faux Pas recognition test (15)13.2±1.5 (9–15)† ‡13.3±1.4 (10.8–13.3)§ 8.4±2.3 (4.1–13.5)† 9.6±2.2 (5.6–14.3)‡ §
Behavioural control (5)3.2±1.2 (0.5–5)† ‡2.5±1.1 (0.5–4)§1.8±1.1 (0–3.5)†1.6±1.5 (0–5)‡ §
Reversal learning (5)3.5±1.9 (0–5)* † ‡2.6±1.9 (0–5)*1.5±1.7 (0–4.5)†1.6±1.5 (0–4)‡
Apathy scale (15)15±0 (15–15)* † ‡11.8±3.6 (6.4–15)* § 9.2±3.6 (2.4–15)† 7.9±2.9 (3.6–15)‡ §
Mini-SEA composite (30)25.8±1.8 (21.6–29.6)† ‡25.7±1.7 (22.8–28.7)§ 18.1±3 (11.8–23.6)† 18±3.8 (11.4–25.4)‡ §

  • Results are expressed as mean±SD (range).

  • ↵* Significant difference between control subjects and MDD. SEA: p<0.001; reversal learning test: p<0.05; apathy scale: p<0.0001.

  • ↵† Significant difference between control subjects and early bvFTD. SEA: p<0.0001; emotion recognition: p<0.0001; Faux Pas test: p<0.0001; apathy scale: p<0.0001.

  • ↵‡ Significant difference between control subjects and moderate bvFTD. SEA: p<0.0001; emotion recognition: p<0.0001; Faux Pas test: p<0.0001; apathy scale: p<0.0001.

  • ↵§ Significant difference between MDD and moderate bvFTD. SEA: p<0.0001; emotion recognition: p<0.0001; Faux Pas test: p<0.0001; behavioural control test: p<0.01; reversal learning test: p<0.05; mini-SEA: p<0.0001.

  • ↵ Significant difference between MDD and early bvFTD. SEA: p<0.0001; emotion recognition: p<0.0001; Faux Pas test: p<0.0001; mini-SEA: p<0.0001.

  • bvFTD, behavioural version of frontotemporal dementia; MDD, major depressive disorder; SEA, Social Cognition and Emotional Assessment.