Neuropsychological test data in FTLD with and without the C9orf72 repeat expansion
| C9orf72 expansion positive FTLD | C9orf72 expansion negative FTLD | p Value | |
|---|---|---|---|
| Age at baseline testing, years | 59.7 (1.4), N=28 | 61.2 (1.2), N=41 | 0.422 |
| Onset to baseline testing interval, years | 3.3 (0.5), N=28 | 3.8 (0.4), N=41 | 0.440 |
| Baseline to follow-up testing interval, months | 14.2 (1.7), N=17 | 15.2 (1.6), N=25 | 0.695 |
| MMSE baseline score | 23.3 (1.4), N=26 | 24.7 (0.9), N=36 | 0.505 |
| MMSE annualised decline | 4.8 (1.2), N=15 | 2.7 (1.1), N=24 | 0.078 |
| Verbal fluency score | 6.2 (0.9), N=19 | 6.4 (0.8), N=28 | 0.777 |
| Verbal fluency annualised decline | 4.5 (1.3), N=10 | 1.4 (0.8), N=16 | 0.023 |
FTLD, frontotemporal lobar degeneration; MMSE, Mini-Mental State Examination.