Group | Invariant | Number of datasets | N*1 | N*2 | Lower 95% CI | Upper 95% CI | Z-value | p Value | Heterogeneity I square (%) | Publication bias |
CC | FA | 15 | 280 | 244 | −0.466 | −0.035 | −2.274 | 0.023 | 27.153 | 0.684 |
ADC | 3 | 39 | 35 | −0.391 | 1.886 | 1.287 | 0.198 | 82.682 | NA | |
MD | 6 | 154 | 100 | 0.062 | 0.581 | 2.425 | 0.015 | 0.000 | NA | |
Genu of CC | FA | 12 | 248 | 218 | −0.537 | 0.224 | −0.805 | 0.421 | 72.933 | 0.535 |
ADC | 3 | 39 | 35 | −0.313 | 2.869 | 1.574 | 0.115 | 89.874 | NA | |
MD | 4 | 132 | 88 | −0.120 | 0.438 | 1.117 | 0.264 | 0.000 | NA | |
Midbody of CC | FA | 9 | 197 | 156 | −0.404 | 0.034 | −1.651 | 0.099 | 4.188 | NA |
Splenium of CC | FA | 15 | 280 | 244 | −0.689 | −0.046 | −2.238 | 0.025 | 65.870 | 0.610 |
ADC | 3 | 39 | 35 | −0.928 | 2.564 | 0.918 | 0.358 | 91.997 | NA | |
MD | 6 | 154 | 100 | 0.113 | 0.950 | 2.490 | 0.013 | 53.164 | NA | |
IC | FA | 8 | 117 | 105 | −0.317 | 0.478 | 0.397 | 0.691 | 46.970 | NA |
CR | FA | 3 | 41 | 57 | −0.564 | 0.272 | −0.684 | 0.494 | 0.000 | NA |
N*1: number of patients of mTBI, N*2: number of control subjects.
ADC, apparent diffusion coefficient; CC, corpus callosum; CR, corona radiata; FA, fractional anisotropy; IC, internal capsule; MD, mean diffusivity