Results of quality of life inventories (in standard values) for sepsis and ICU patients compared to historical norms
Sepsis | ICU | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Statistical testing | Statistical testing | |||||||||
n | M | SE | t | p | n | M | SE | t | p | |
SCL-90-R* | ||||||||||
Somatisation | 24 | 111.94 | 0.451 | 26.485 | <0.001 | 16 | 110.42 | 0.394 | 26.429 | <0.001 |
Obsessive compulsive | 24 | 110.74 | 0.347 | 30.970 | <0.001 | 16 | 110.11 | 0.322 | 31.385 | <0.001 |
Interpersonal sensitivity | 24 | 110.16 | 0.262 | 38.798 | <0.001 | 16 | 109.52 | 0.149 | 63.853 | <0.001 |
Depression | 24 | 110.68 | 0.367 | 29.070 | <0.001 | 16 | 109.82 | 0.237 | 41.388 | <0.001 |
Anxiety | 24 | 110.77 | 0.366 | 29.466 | <0.001 | 16 | 109.82 | 0.300 | 32.703 | <0.001 |
Hostility | 24 | 109.94 | 0.175 | 56.821 | <0.001 | 16 | 109.76 | 0.167 | 58.515 | <0.001 |
Phobic anxiety | 24 | 110.85 | 0.440 | 24.680 | <0.001 | 16 | 110.58 | 0.577 | 18.325 | <0.001 |
Paranoid ideation | 24 | 110.06 | 0.219 | 45.987 | <0.001 | 16 | 109.81 | 0.212 | 46.276 | <0.001 |
Psychoticism | 24 | 110.60 | 0.389 | 27.278 | <0.001 | 16 | 110.01 | .267 | 37.494 | <0.001 |
Global severity index | 24 | 110.93 | 0.422 | 25.898 | <0.001 | 16 | 109.96 | 0.310 | 32.112 | <0.001 |
SF-36† | ||||||||||
Physical function | 24 | 104.40 | 0.353 | 12.502 | <0.001 | 18 | 104.78 | 0.411 | 11.631 | <0.001 |
Role physical | 24 | 104.98 | 0.341 | 14.599 | <0.001 | 18 | 104.88 | 0.401 | 12.153 | <0.001 |
Bodily pain | 24 | 105.20 | 0.249 | 20.869 | <0.001 | 18 | 105.11 | 0.343 | 14.920 | <0.001 |
General health | 24 | 107.66 | 0.211 | 36.384 | <0.001 | 18 | 107.82 | 0.238 | 32.914 | <0.001 |
Vitality | 24 | 108.06 | 0.176 | 45.910 | <0.001 | 18 | 107.98 | 0.096 | 83.456 | <0.001 |
Social function | 24 | 105.04 | 0.239 | 21.125 | <0.001 | 18 | 105.10 | 0.210 | 24.274 | <0.001 |
Role emotional | 24 | 105.75 | 0.311 | 18.479 | <0.001 | 18 | 105.81 | 0.320 | 18.151 | <0.001 |
Mental health | 24 | 107.82 | 0.213 | 36.772 | <0.001 | 18 | 107.83 | 0.128 | 61.280 | <0.001 |
Physical health sum | 24 | 105.63 | 0.103 | 54.561 | <0.001 | 18 | 105.69 | 0.098 | 58.209 | <0.001 |
Mental health sum | 24 | 106.71 | 0.162 | 41.511 | <0.001 | 18 | 106.72 | 0.077 | 87.572 | <0.001 |
BDI‡ | 24 | 110.55 | 0.272 | 38.785 | <0.001 | 18 | 110.07 | 0.230 | 43.859 | <0.001 |
Scales are negatively poled so that a higher score indicates lower quality of life or lower functioning. Comparison of means to historical norms by one sample two-tailed Student t test; Bonferroni correction for multiple comparisons (α=0.001). MANCOVA of SF-36 scores with length of hospitalisation and APACHE II as covariates revealed a significant group differences for Role Emotional (F(1,26)=8.219; p=0.008, ηp2=0.240). The multivariate test was significant (Wilks-Lamda = 0.333; F(8,19)=4.760; p=0.002). Bold type indicates statistically significant differences.
*SCL-90-R Norm data: (N=2141).29
†SF-36 Norm data: (N=2000).28
‡BDI Norm data: (N=86).30
APACHE, acute physiology and chronic health evaluation; BDI, Beck Depression Inventory; ICU, intensive care unit; MANCOVA, multivariate analysis of covariance. SCL-90-R, Symptom Check List-90-R; SE, septic encephalopathy; SF-36, Short Form-36 Health Survey.