Frequency of adverse events over the study
| AEs occurring between | Cannabis extract (N=143) | Placebo (N=134) | Cannabis extract compared with placebo |
| n (%) | n (%) | p Value* | |
| Visits 2 and 3 | 108 (75.5) | 51 (38.1) | <0.001 |
| Visits 3 and 4 | 66 (46.2) | 42 (31.3) | 0.012 |
| Visits 4 and 5 | 49 (34.3) | 39 (29.1) | 0.357 |
| Visits 5 and 6 | 43 (30.1) | 42 (31.3) | 0.819 |
↵* Cochran–Mantel–Haenszel–χ2 test (α=0.05, two sided).
AE, adverse event; %, percentage (based on N); n, number of patients with events in specified category; N, number of patients in specified treatment group.