General characteristics of patients
Age of diagnosis (years) | Age of starting GCs (years) | Duration of treatment (years) | Dose of GCs (mg/kg/day) | Duration of follow-up (years) | |
---|---|---|---|---|---|
A | |||||
IP (n=154) | 4.4 (0.3–9.4) | 6.5 (4.2–9.6) | 3.6 (0.5–8.5) | 0.6 (0.3–0.8) | 2.5 (0.2–5.4) |
DP (n=136) | 4.3 (0.3–9.4) | 6.2 (4.2–9.8) | 4.3 (0.5–7.5) | 0.5 (0.3–0.8) | 2.7 (0.3–7.8) |
SW (n=72) | 4.2 (0.2–8.6) | 6.3 (3.4–9.2) | 4.1 (0.7–7.8) | 0.6 (0.3–0.8) | 3.2 (0.4–6.9) |
DFZ (n=19) | 5.5 (0.5–8.7) | 7.0 (5.2–9.3) | 4.4 (0.6–7.9) | 0.6 (0.4–0.9) | 2.8 (0.6–7.0) |
AD (n=15) | 4.4 (1.3–8.2) | 6.3 (4.4–9.0) | 5.0 (2.4–7.5) | 0.6 (0.3–0.8) | 2.0 (0.2–3.9) |
Not on GCs (n=32) | 3.3 (0.9–6.9) | – | – | – | – |
IP | DP | DFZ | AD | ||
B | |||||
Starting regimen | 57 | 12 | 2 | 1 | |
Majority of treatment | 37 | 33 | 1 | 1 | |
Age of switching regimen (years), mean (range) | 8.4 (5.6–12) | 8.5 (7.3–9.3) | – | – |
(A) Summary of patients’ characteristics presented as mean (range) (n=428): age of diagnosis, age of starting steroids, duration of treatment, dose of steroids during the whole duration of treatment, and duration of follow-up since registration on the database. (B) Switchers (n=72): in the analysis, 70 switchers were included as per majority of treatment for intermittent and daily regimens.
AD, prednisolone on alternate days; DFZ, deflazacort; DP, daily prednisolone; GC, glucocorticoid corticosteroids; IP, intermittent prednisolone 10 days on/10 days off; SW, switcher.