Patient characteristics at time of recruitment
| Measure | Transplant | Controls | t15* |
|---|---|---|---|
| n | 5 | 12 | |
| Sex (M:F) | 4 : 1 | 8 : 4 | |
| Age at recruitment | 43.4±1.5 | 47.2±2.7 | 2.11 |
| Age at transplant | 48.0±1.5 | 51.1±2.1 | 0.88 |
| Education age | 13.8±0.69 | 12.3±0.7 | 1.27 |
| UHDRS | 23.4±6.0 | 19.3±3.2 | −0.87 |
| Total functional assessment | 27.0±0.7 | 26.2±0.5 | 0.80 |
| Total functional capacity | 10.4±0.8 | 10.8±0.6 | 0.36 |
| Independence score | 94.0±1.6 | 94.6±3.2 | 0.11 |
| Mini mental state exam | 28.8±0.3 | 27.8±0.7 | 0.88 |
| WAIS (vocab) | 11.2±0.8 | 10.1±0.7 | −1.45 |
| WAIS (block design) | 11.0±1.2 | 10.7±0.7 | −0.33 |
| NART | 115.0±1.1 | 109.6±2.1 | −3.19* |
| VOSP battery (total score) | 132.6±2.8 | 129.8±3.3 | −0.93 |
| VOSP battery (n of pass) | 1.0±0.6 | 1.3±0.4 | 0.62 |
| Boston naming test | 28.0±0.4 | 26.8±0.4 | −2.80 |
| Token test | 33.8±0.9 | 32.7±0.5 | −1.53 |
*All differences are non-significant at p>0.10, with the exception of the NART scores, p<0.01.
N.B: As patient recruitment took place more than 12 years ago, while genetic confirmation of the HD gene expansion was obtained for all participants, the exact CAG repeat length was not documented in many cases.
UHDRS, Unified Huntington's Disease Rating Scale; WAIS, Wechsler Adult Intelligence Scale; VOSP, visual object and space perception battery; NART, National Adult Reading Test.