Univariate analysis of recurrent stroke risk factors
| Arterial territory | HR (95% CI) | Other territory | HR (95% CI) | |||
|---|---|---|---|---|---|---|
| Yes | No | Yes | No | |||
| Number of patients | 7 | 123 | 6 | 124 | ||
| Age, mean±SD, y | 66±5 | 64±8 | 1.03 (0.94 to 1.12) | 68±5 | 64±8 | 1.07 (0.97 to 1.17) |
| Sex, male, number (%) | 6 (86) | 97 (79) | 1.6 (0.2 to 13.8) | 3 (50) | 100 (81) | 0.26 (0.05 to 1.32) |
| Recurrent symptoms | 4 (57) | 48 (39) | 2.0 (0.4 to 9.0) | 2 (33) | 50 (40) | 0.78 (0.14 to 4.3) |
| After demonstration of arterial disease | 2 (29) | 23 (19) | 1.7 (0.3 to 8.9) | 1 (17) | 24 (19) | 0.88 (0.1 to 7.5) |
| Number of months between last symptom and PET, mean±SD | 18±23 | 8±15 | 1.02 (0.99 to 1.05) | 3±4 | 8±16 | 0.96 (0.85 to 1.07) |
| Recent (6 m or less) | 4 (57) | 96 (78) | 0.38 (0.08 to 1.73) | 5 (83) | 95 (77) | 1.43 (0.16 to 12.2) |
| Arterial occlusion | 3 (43) | 83 (67) | 0.38 (0.08 to 1.70) | 3 (50) | 83 (67) | 0.48 (0.09 to 2.39) |
| Extracranial ICA occlusion | 3 (43) | 58 (47) | 0.86 (0.19 to 3.85) | 3 (50) | 58 (47) | 1.14 (0.23 to 5.67) |
| Hypertension | 6 (86) | 72 (59) | 4.1 (0.49 to 34.2) | 4 (67) | 74 (60) | 1.4 (0.26 to 7.7) |
| Diabetes mellitus | 3 (43) | 44 (36) | 1.3 (0.3 to 6.0) | 3 (50) | 44 (35) | 1.8 (0.1 to 7.3) |
| Ischaemic heart disease | 3 (43) | 24 (20) | 3.0 (0.6 to 13.7) | 1(17) | 26(21) | 0.8 (0.6 to 13.7) |
| Hypercholesterolaemia | 2 (29) | 38 (31) | 0.87 (0.16 to 4.5) | 2 (33) | 38 (31) | 1.07 (0.19 to 5.8) |
| Smoking (current and former) | 4 (57) | 42 (34) | 2.4 (0.54 to 10.8) | 2 (33) | 44 (35) | 0.9 (0.16 to 4.9) |
| SBP | ||||||
| Categorisation | 1.4±0.7 | 2.2±0.8 | 0.27 (0.08 to 0.93) | 3.3±0.8 | 2.1±0.8 | 4.02 (1.4 to 10.8) |
| Normal BP | 5 (71) | 27 (22) | 8.1 (1.5 to 41.8) | 0 (0) | 26 (21) | NE |
| Decreased CBF/CBV | 6 (86) | 33 (27) | 15.0 (1.8 to 125.0) | 1 (17) | 38 (31) | 0.5 (0.06 to 4.4) |
| Misery perfusion | 4 (57) | 12 (10) | 10.1 (2.2 to 45.2) | 0 (0) | 16 (13) | NE |
Categorisation=1, <130; 2, 130–149; 3, 150–169; 4, ≥170 mm Hg.
BP, blood pressure; CBF, cerebral blood flow; CBV, cerebral blood volume; ICA, internal carotid artery; NE, not estimable; PET, positron emission tomography; SBP, systolic blood pressure.