Prevalence of neurodevelopmental disorders by dose of sodium valproate
| Valproate combined† (n=70) | Valproate monotherapy (n=50) | Valproate polytherapy (n=20) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Dose of valproate mg/daily* | Yes | No | % | Yes | No | % | Yes | No | % |
| 2000–3000 | 2 | 2 | 50 | 0 | 1 | 0 | 2 | 1 | 66.7 |
| 1000–1900 | 5 | 28 | 15.2 | 4 | 22 | 15.4 | 1 | 6 | 14.3 |
| 100–900 | 2 | 31 | 6.5 | 2 | 21 | 8.7 | 0 | 10 | 0 |
*Preconception dose.
†Monotherapy and polytherapy combined.