Characteristics predicting a poor outcome among 90 subjects with Marchiafava–Bignami disease (MBD) treated with thiamine
| Characteristic | Univariable OR (95% CI) | Multivariable OR (95% CI) |
|---|---|---|
| Age (per year) | 1.02 (0.98 to 1.06) | 1.02 (0.97 to 1.06) |
| Men | 0.82 (0.29 to 2.32) | 0.51 (0.14 to 1.80) |
| Loss of consciousness | 1.29 (0.52 to 3.19) | 1·70 (0.62 to 4.70) |
| Seizures | 1.23 (0.43 to 3.49) | 1.28 (0.39 to 4.14) |
| Alcoholism | 2.74 (0.31 to 23.90) | 1.69 (0.12 to 22.90) |
| Steroid treatment | 1.71 (0.54 to 5.41) | 1.49 (0.39 to 5.65) |
| Lesion locations† | 4.62 (0.99 to 21.63) | 4.27 (0.76 to 24.07) |
| Delayed thiamine treatment | 2.80 (1.07 to 7.34)* | 2.91 (1.02 to 8.36)* |
*p<0.05.
†A solitary splenial lesion is used as a reference category for the other locations. Subjects without a risk factor serve as a reference category for the independent factors.