Ropper1 | Arai et al4 | Capasso et al14 | Chan et al5 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Patient 1 | Patient 2 | Ropper3 | Mizoguchi et al9 | Kashihara et al10 | Osaki et al11 | Okuda et al12 | Pan et al13 | Patient 1 | Patient 2 | Patient 1 | Patient 2 | ||
Age, sex | 19, M | 54, F | 23, F | 40, M | 55, F | 26, M | 21, M | 37, F | 65, M | 41, M | 47, M | 67, M | 61, F |
Ptosis | + | + | + | − | + | + | − | − | − | − | − | − | + |
External ophthalmoparesis | + | − | ++ | + | + | + | − | − | − | + | − | − | ++ |
Internal ophthalmoparesis | + | − | − | − | + | − | − | − | − | − | − | − | − |
Facial palsy | ++ | + | + | + | + | + | + | − | − | + | − | + | − |
Oropharygneal palsy | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ |
Neck weakness | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | + | ++ |
Upper limb | |||||||||||||
Weakness | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ |
Hypo- or areflexia | + | + | + | − | + | + | + | + | + | + | + | + | + |
Lower limb | |||||||||||||
Weakness | + | + | + | + | − | + | + | − | − | + | + | + | − |
Hypo- or areflexia | − | + | + | − | + | + | + | − | + | + | − | + | + |
Ataxia | − | − | + | − | − | − | − | − | − | − | − | + | + |
Our diagnosis | PCB | PCB | PCB/FS | PCB | PCB | PCB | PCB | PCB | PCB | PCB | PCB | PCB/AAN | PCB/FS |
−, normal; +, mild ophthalmoplegia or weakness; ++, marked ophthalmoplegia or weakness; /, overlap syndrome.
AAN, acute ataxic neuropathy; FS, Fisher syndrome.