Summary of patient clinical and demographic data according to autoimmune cohort
| Secondary autoimmunity | No secondary autoimmunity | |
|---|---|---|
| Gender, the female to male ratio | 3:1 | 1.5:1 |
| Pretreatment annualised relapse rate | Mean 1.8 Range 0.5–3.5 | Mean 1.9 Range 1.0–4.5 |
| Age at first treatment | Mean 31.2 years Range 17–48 years | Mean 32.9 years Range 17–62 years |
| Type of secondary autoimmune disease (% of sum patients) | Thyroid 35% ITP 1.4% Goodpasture's 0.7% Others* 1.4% | – |
| Number of treatment cycles before onset of autoimmunity | Median 2 Range 1–3 | – |
| Time from baseline treatment to onset of autoimmunity | Mean 33 months Range 9–79 months | – |
*Others: autoimmune hepatitis and anti-neutrophil antibody neutropaenia.
ITP, idiopathic thrombocytopenic purpura.