Kaplan–Meier survival analysis
| Total relapses=1–2 | Total relapses=3–4 | Total relapses ≥5 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean (median) years from disease onset to DSS 8 | |||||||||
| Duration of RR phase (years) | n (% censored) | p Value | n (% censored)) | p Value | n (% censored) | p Value | |||
| 1–5 | 57 (28) | 20.0 (17) | <0.001 | 30 (20) | 13.7 (10) | <0.001 | 31 (25) | 15.1 (11) | <0.001 |
| 6–12 | 50 (26) | 25.0 (23) | <0.001 | 48 (31) | 21.5 (21) | <0.001 | 52 (23) | 18.9 (19) | <0.001 |
| ≥13* | 37 (35) | 34.0 (33) | 45 (40) | 34.2 (31) | 71 (54) | 34.7 (33) | |||
| Total | 144 | 123 | 154 | ||||||
Estimated mean times to bed bound status (DSS 8) among patients stratified by number of total attacks during the RR phase and latency to progression (duration of RR phase).
*Reference category.
DSS, Disability Status Scale; RR, relapsing remitting.