CPAP+ (n=14) | CPAP− (n=9) | p Value | |
---|---|---|---|
Age (years)* | 73.4 (68; 79.6) | 77.6 (74.8; 79.4) | 0.17 |
Gender ratio H/F | 10/4 | 4/5 | 0.38 |
Educational level (0/1) | 6/8 (42.9%/57.1%) | 7/2 (77.8%/22.2%) | 0.19 |
MMSE at baseline* | 23.5 (20; 27) | 20 (16; 24) | 0.09 |
AHI* | 47.7 (36.7; 62.6) | 43.3 (37.2; 51.2) | 0.52 |
BMI (kg/m2)* | 26.7 (24.7; 28.3) | 24.5 (23.0; 33.1) | 0.81 |
Vascular risk factor (at least 1) | 10 (71.4%) | 7 (77.8%) | 1 |
Hypertension | 10 (71.4%) | 7 (77.7%) | 0.88 |
Diabetes | 2 (14.3%) | 3 (33.3%) | 0.57 |
Dyslipidaemia | 8 (57.1%) | 6 (66.6%) | 0.98 |
Smoking | 10 (71.4%) | 3 (33.3%) | 0.17 |
Heart disease | 9 (20.5%) | 3 (33.3%) | 0.3 |
Antihypertensive drugs | 8 (57.1%) | 7 (77.8%) | 0.39 |
Statin | 6 (42.9%) | 5 (55.6%) | 0.68 |
Antiplatelet agent | 8 (57.1%) | 5 (55.6%) | 1 |
Cholinesterase inhibitor | 13 (92.8%) | 9 (100%) | 0.81 |
Memantine | 9 (64.2%) | 8 (88%) | 0.40 |
Duration of follow-up (years)† | 3.3 (1.8; 3.6) | 3.0 (2.3; 3.6) | 1 |
*Median (range).
†Median (IQR).
AD, Alzheimer's disease; AHI, apnoea hypopnoea index; BMI, Body Mass Index; educational level 0, patients without any formal education or having completed only primary school education; educational level l, patients having completed middle school or high school education; CPAP−, patients who refused continuous positive airway pressure; CPAP+, patients who accepted continuous positive airway pressure; MMSE, Mini Mental State Examination; PSG, polysomnography; SAS, sleep apnoea syndrome.