Table 2

Experimental task performance of patient and healthy control groups

C9ORF72MAPTSporadic-FTDHealthy controls
Tactile discrimination
 Number completing test5639
 Mean (SD) threshold (mm)18.5 (4.1)*13.4 (2.6)10.3 (6.5)13.1 (3.2)
 Range thresholds (mm)12–239–164–186–18
Tendon vibration
 Number completing test45412
Baseline accuracy
 Mean (SD) angle† score (degrees)4.8 (3.4)5.8 (5.4)6.7 (4.2)2.4 (2.0)
 Range angle scores (degrees)0.8–9.20.3–13.53.1–12.60.6–6.3
Stimulation accuracy
 Mean (SD) angle score (degrees)15.5 (18)7.01 (3.2)4.84 (3.8)3.8 (3.7)
 Range angle scores (degrees)4–434–111–90–10
Rubber hand illusion
 Number completing test47413
 Mean questionnaire score5 (1.8)*17.3 (5.2)16.5.4 (6.8)13.1 (7.1)
 Range questionnaire scores3–79–217–213–21
Self-non-self action attribution
 Number completing test56513
Tickle self
 Mean (SD) score (/10)7.2 (2.2)*9.8 (0.4)10 (0)9.8 (0.3)
 Range scores5–109–10109–10
Tickle non-self synchronous
 Mean (SD) score (/10)4 (0.7)5.5 (1.5)5.4 (3.4)4.6 (3.2)
 Range scores3– 53–71–100–9
Tickle non-self asynchronous
 Mean (SD) score (/10)6.2 (3.5)9.1 (1.2)8.8 (2.7)9.9 (0.2)
 Range scores1–97–10109–10
  • Mean (SD) values shown for experimental task performance. Scores statistically different from control group performance at p<0.05 are in bold.

  • *Also significantly different from both other patient groups; C9ORF72, pathogenic expansions associated with C9ORF72; FTD, frontotemporal dementia; MAPT, pathogenic mutations in the microtubule-associated protein tau gene.

  • †All angle values are based on individual absolute mean values of deviation angle (see figure 2).