Demographic, apolipoprotein and lipid profile characteristics (mean±SD)
| Characteristic | Value | Reference interval* |
|---|---|---|
| Females to males (% female) | 123:58 (68%) | |
| Age, years | 28.7±8.1 | |
| HDL cholesterol, mg/dL | 68±20 | 40–83 |
| LDL cholesterol, mg/dL | 130±41 | 57–189 |
| Total cholesterol, mg/dL | 200±56 | 133–234 |
| Triglycerides, mg/dL | 108±50 | 37–321 |
| Apolipoprotein B, mg/dL | 71.1±25 | 60–130 |
| Apolipoprotein AI, mg/dL | 154±41 | 115–224 |
| Apolipoprotein AII, mg/dL | 36.4±9.0 | 25–35 |
| Apolipoprotein E, mg/dL | 3.21±1.1 | 3.3–6.1 |
| Lipoprotein a, mg/dL | 12.6±13 | <30 |
| C reactive protein, mg/L | 2.63±4.1 | <2.5 |
| BMI, kg/m2 | 24.0±3.9 | |
| Active smokers (%)† | 59/181 (33%) | |
| HLA DRB1†1501 positive‡(%) | 83/171 (49%) |
The apolipoprotein and lipid profile variables were obtained prior to corticosteroid or interferon β-1a treatment.
*Normal range in presumably healthy adults provided by diagnostic reagent kit manufacturers.
†Active smoking status was assessed using serum cotinine levels.18
‡Genotypes not available for 10 patients.
BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein.