Table 1

Characteristics and behavioural subscale scores in HD mutation carriers of the REGISTRY study

REGISTRY participants (n=1993)
Sociodemographics
 Sex, male1019 (51.1)
 Age, years50.3±12.3
Clinical characteristics
 CAG repeat length, number44.6±4.3
  Duration of disease, years*5.9 (3.4–9.9)
  TMS, points35.3±19.8
  TFC, points8 (5–12)
  Disease stage
   Stage 1662 (33.2)
   Stage 2655 (32.9)
   Stage 3513 (25.7)
   Stage 4140 (7.0)
   Stage 523 (1.2)
Psychotropic medication use
 Any psychotropics†1117 (56.0)
  Benzodiazepines‡338 (17.0)
  Antidepressants§692 (34.7)
  Antipsychotics¶679 (34.1)
  Mood stabilisers/antiepileptics**144 (7.2)
Behavioural subscale scores
 Depression, points3 (0–10)
 Irritability/aggression, points1 (0–5)
 OCBs, points0 (0–3)
 Apathy, points1 (0–6)
 Psychosis, points0 (0–0)
  • Data are presented as n (%), mean (±SD) or median (IQR) when appropriate.

  • *Duration of disease is calculated by date of visit minus the rater-estimated date of disease onset.

  • †111 missings.

  • ‡78 missings.

  • §85 missing.

  • ¶69 missings.

  • **19 missings due to missing values for use of psychotropics.

  • HD, Huntington's disease; OCBs, obsessive/compulsive behaviours; TFC, Total Functional Capacity; TMS, Total Motor Score.