Table 3

Demographics and the proportion of cases in each group with the main clinical features of the new FTD clinical phenotypes

FTLD (N=102)AD (N=33)p Value
% male/% female64/3673/270.211
Age at onset (years)58 (9)64 (10)0.002
Age at diagnosis (years)62 (8)68 (9)0.002
Age at death (years)68 (9)74 (8)0.003
Duration from onset (years)10 (4)10 (6)0.884
Duration from diagnosis (years)6 (3)6 (3)0.889
Behavioural features
 Loss of empathy2918
 Stereotyped behaviours7748
Alt. food pref.5524*
 Executive deficits4021
Language features
Word finding6185*
 Apraxia of speech1633
 Single word comp2724
Object agnosia113*
Phonologic errors1258*
 Word rep842
Sentence rep1042*
 Sentence Comprehension4758
 Surface dyslexia3664
Motor features
Gait disturbance718*
 Orobuccal apraxia83
Neuropsychiatric features
Other features
 Rigidity of thought3424
  • *Features with high (>80%) and low (<20%) prevalences indicated and the patterns of features discriminating pathology type statistically identified in bold (Wilks’ lambda=0.596, p<0.0001).

  • AD, Alzheimer's disease; FTD, frontotemporal dementia; FTLD, frontotemporal lobar degeneration.