Table 6

APOE allele frequencies according to age (age at onset for patients and age at inclusion for healthy controls)

 Age (years)nAllele frequencies (%)
ε2ε3ε4
DLB≤65303.360.036.7*
66–791004.0*62.034.0*
≥802611.569.319.2
AD≤651444.541.354.2*
66–792634.7*50.844.5*,†
≥801129.8‡65.624.6*,‡
Healthy controls≤655910.272.017.8
66–794269.976.313.8
≥8015812.772.714.6
  • *Significant difference between a patient group and the control group.

  • †Significant difference between the groups of patients with DLB or AD.

  • ‡Significant difference in allele frequency according to age within the respective group (Pearson's χ2 test).

  • AD, Alzheimer's disease; DLB, dementia with Lewy bodies.