Characteristics of patients with and without disability progression in the first year after delivery
| With disability progression (#44) | Without disability progression (#294) | p Value | |
|---|---|---|---|
| Age at conception (mean, SD, years)* | 31.5 (6.2) | 31.8 (4.5) | 0.747 |
| Age at onset (mean, SD, years)* | 24.1 (7.7) | 24.8 (5.5) | 0.609 |
| Disease duration at conception (mean, SD, years)* | 7.4 (5.2) | 7.1 (4.8) | 0.701 |
| EDSS at conception (median, IQR)† | 1.5 (1.0–2.5) | 1.5 (1.0–2.0) | 0.366 |
| Treated with DMDs prior to pregnancy (#, %)‡ | 26 (59.1) | 147 (50) | 0.261 |
| Smoking during pregnancy (#, %)‡ | 3 (6.8) | 21 (7.1) | 0.938 |
| Relapses in the year prior to pregnancy (median, IQR)† | 0 (0–1) | 0 (0–0) | 0.006 |
| Relapses during pregnancy (median, IQR)† | 0 (0–0) | 0 (0–0) | 0.390 |
| Relapses in the year after delivery (median, IQR)† | 1 (1–2) | 0 (0–1) | 0.005 |
| Exclusive breast feeding (#, %)‡ | 13 (29.5) | 106 (36.1) | 0.403 |
| Early DMDs introduction (#, %)‡ | 11 (25.0) | 58 (19.7) | 0.418 |
*Student t test.
†Mann–Whitney U test.
‡Pearson's χ2 test.
DMDs, disease modifying drugs; EDSS, Expanded Disability Status Scale.