Table 1

Demographic data for the study groups

DLB (total)DLB (TrønderBrain)DLB (DemVest)AD (TrønderBrain)Healthy controls (TrønderBrain)
Cases (total)15610353519643
Probable/possible DLB135/2188/1547/6
Females (%)67 (42.9)*,44 (42.7)23 (43.4)351 (67.6)*388 (60.3)
Age at onset (y)72.3±7.972.3±7.772.1±8.371.3±9.3NA
Age at inclusion (y)76.3±7.6*76.9±7.775.3±7.476.0±9.9*74.8±7.2
Duration (y)4.2±3.0†4.5±3.13.5±2.54.7±3.2NA
Range of onset (y)46–8946–8850–8947–88NA
Mean education (y)9.8±3.19.9±3.19.6±3.09.5±3.1*9.8±2.9
MMSE19.6±7.517.9±8.4‡22.9±3.317.8±8.1†NA
UPDRS III16.9±12.9†18.7±12.3‡13.9±13.63.3±6.0 (n=294)NA
  • Statistical analysis was initially made using the Kruskal–Wallis test for multiple groups. Where values of p<0.05 were found, subsequent individual group comparisons were made with the Mann–Whitney U test.

  • All p values ≤0.03.

  • *Significant difference between a patient group and the control group.

  • †Significant difference between the groups of patients with DLB or AD.

  • ‡Significant difference between the two DLB cohorts.

  • AD, Alzheimer's disease; DLB, dementia with Lewy bodies; MMSE, Mini Mental State Examination; UPDRS, Unified Parkinson's Disease Rating Scale.