Table 2

Percentage of patients with each binary outcome at each annual follow-up over three years

Binary outcome categoryAnnual follow-up appointmentOverall p Value
BaselineYear 1Year 2Year 3
n (%)n (%)n (%)n (%)
H-Y stage ≥30/147 (0)16/132 (12.1)30/134 (22.4)28/127 (22.0)0.047
S&E <80%0/151 (0)21/144 (14.6)34/136 (25.0)37/130 (28.5)0.045
‘Dead or dependent’0/151 (0)28/151 (18.5)48/150 (32.0)58/151 (38.4)0.027
  • The ‘n’ column indicates the number of patients in the stated binary category compared with the total number of patients who contributed data relevant to that binary variable at each time point. The % column indicates the actual (not modelled) percentage of patients in the stated binary category at each annual follow-up. The overall P values, derived from generalised estimating equations, relate to the significance of the change in each variable over three years.

  • H-Y, Hoehn-Yahr scale; S&E, Schwab and England Activities of Daily Living Scale.